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Description
Frontiers Semaglutide ameliorates metabolism and hepatic outcomes in an NAFLD mouse model GLP 1 Drugs and Eating Disorders: A Hidden Risk in the Weight Loss Revolution The Chicago Council on Science and Technology Many people starting GLP 1 weight loss medications expect appetite changes but digestive changes like constipation can sometimes catch patients off guard. What many people don't realize is that it's often not caused GLP 1 and Dual GIP GLP 1 Agonists for Obesity: Are They Right for You? TRIUMPH 1: #retatrutide topline data Phase 3, n=2,339, 80 wk, obesity without diabetes (efficacy estimand): 12 mg: 28.3% body weight ( 31.9 kg) 9 mg: 25.9% 4 mg: 19.0%
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4.5 ★★★★★
Based on 707 reviews
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Product Reviews
★★★★★ 5
This company makes great toys for pitts!!
Color: Blue/Medium, Size: Blue, Color: Blue/Medium, Size: Blue
Our pitt LOVES this toy. The rubber is reeeaally tough. It’s well designed because it’s a slippery surface. You can tell from the video there’s a lot of squeaking from him trying to get a good grip. He found a pretty good spot to hook his upper teeth into the crevasse, but his bottom teeth kept slipping.
As a side note, I wouldn’t leave any toy home alone with him that’s about 3 inches or smaller because dogs can choke on it, but that doesn’t make this any toy or company any less amazing. For toys I would leave home with a power chewer, take a look at that 4inch red ball made by this same company. He hasn’t made a dent in that thing and you can put treats in it. :)
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Reviewed in the United States on March 5, 2025
★★★★★ 1
No for aggressive chewer waste of money
Color: Blue/Medium, Size: Blue, Color: Blue/Medium, Size: Blue
Within 10 minutes she destroyed it
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Reviewed in the United States on June 1, 2026
★★★★★ 5
Favorite toy!
Color: Orange/Large, Size: Orange
My dog lives these!
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Reviewed in the United States on April 23, 2026
★★★★★ 5
Takes a beating - looks like new!
Color: Blue/Medium, Size: Blue
EDITED AGAIN, 12/28/22:
My boy still has his original blue one of these and the yellow one from way back. He's received a couple more over the years which he's managed to sneak out of the house and lose - evidently neighbor dogs or perhaps foxes, etc love them, too, and carry them off?! At any rate, he'd managed to get himself back to his original two, so I bought him a late Christmas present of a new yellow bone. He just opened the package (with help, of course - he's smart, but lacks the necessary opposing thumbs to do it on his own) and he was ecstatic! He reached into the mailing envelope, grabbed it, gave it a couple of triumphant tosses then ran for his bed, pulled a blanket in, and has been chewing, fighting with, burying in the blanket and "discovering" it for about a half hour now! I don't know what the attraction is, but he still loves these things and they're still lasting! The only other toys that have lasted more than a day are Nylabones (because he won't even look at them, let alone touch them) and a set of interlocked skinny rubber rings that he's not at all interested in, but if I ask about them, he'll move them around the room for a couple of days to make me feel better! LOL
EDITED TO ADD 2022:
Here I am, back 5 1/2 years later to say my dog STILL has this bone and makes use of it a couple of times a week. And he still loves it and sleeps with it. He has gone through a couple of the smaller version (yellow instead of blue) over this time frame because those get constant use. But that’s amazing in itself!! These are still the only toy I would call indestructible.
Great toy! I have a dachshund who destroys toys in record time. I can hear the amused chuckles now, but anyone who has seen him in action (including rottie, pit bull and Doberman owners) is in awe. He is very methodical and relentless - the mad genius of dog toy torture! Small and quiet but utterly ruthless.
Anyway...my boy has been working on this since the beginning of October and the thing looks like new! I think you can see one tooth mark, otherwise it looks untouched! This is a dog who can reduce Kongs and other rubber toys to a pile of chunks in minutes.
But he also LOVES it - carries it around, brings it into his bed at night to sleep, and when his doxie brother (who is far too dignified to do dog toys) doesn't feel well, it is offered up as a "feel better" snuggly...for about 2 minutes. But it's the thought that counts, right?
I don't know what makes this so attractive to my mini-Jaws and so long-lasting, but it works!
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Reviewed in the United States on February 3, 2017
★★★★★ 5
HEAVEY Duty!
Color: Blue/Medium, Size: Blue
Almost not destructible! My dogs chew through 99% of the toys we purchase, but never this one! The medium size is good for our Doberman with jaws of steel!
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Reviewed in the United States on May 4, 2026
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