SKU: 690677477

NMN Pro™ Powder - Uthever® NMN, 500 grams

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Description

NMN Pro™ Powder - Uthever® NMN, 500 gramsHelps combat aging, improves heart health and promotes muscle strength NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression. Nicotinamide mononucleotide (NMN) is a derivative of the B vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+. NMN Pro Powder allows NMN to be

Helps combat aging, improves heart health and promotes muscle strength

  • NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.
  • NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.

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Research-Supported Benefits:

Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies.1

Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders.2

Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight.3,4,5

Supports Healthy Cognition: Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction.6,7

Supports Healthy Skin: In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance.8,9

References:

1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004 

2. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004 

3. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287 

4. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080/08982104.2020.1820521 

5. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016/j.jphotobiol.2021.112238 

6. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755 

7. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5 

8. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442- 

9. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013 

10. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192 

11. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016/j.brainres.2016.04.060 

12. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016/j.cmet.2011.08.014 

13. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985

  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.
  • NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.
Supplement Facts

Serving Size: 1 Level Scoop

Servings Per Container: 500
Amount Per Serving %DV
Uthever® β-Nicotinamide Mononucleotide (NMN)
1 g
† Daily Value not established.
REV.07.23
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • SUGGESTED DAILY USE: Place 1 level scoop under the tongue to dissolve then swallow, or mix in cold water or other beverage, or as recommended by your healthcare professional. 
  • CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
  • NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. Package filled by weight, not volume. KEEP OUT OF REACH OF CHILDREN.

Only Clinically-Proven NMN. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.

Unique Delivery Method. NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability.

Solvent-Free. Compared to other NMN products, ours is made without any chemical solvents.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

Be Aware of Fake NMN: Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.

Shipping Notes
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Exchange/Return Notes
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  • To process your return/exchange, please contact us at [email protected]
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Great references book.
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Excellent book for medical reference and refresh of knowledge.
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Ray Schaar
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A Wonderful Update To A Great Old Reference Book!
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It's the Merck Manual! If you know medicine but are aware you don't know EVERYTHING about EVERYTHING! (Few if any do!) This is a wonderful reference. If you have no medical knowledge and think this will make you know what doctors know. Don't waste your money. You have to have a basic understanding for this to be helpful. This is a wonderful update to an old favorite.
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Majted
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The most current and inclusive medical reference available mid-2018.
Format: Hardcover, Format: Hardcover
Here’s the review I wrote for the 19th edition on 2011: I've been getting and using the Merck Manual for over 30 years to answer questions about disease for family and friends (pediatrics through geriatrics) as well as preparing to ask germane questions of physicians responsible for care of family and friends. It is comprehensive in its coverage of the etiology, diagnosis, treatment and prognosis of diseases of the human body and contains the latest research results on the treatment options. It's really not that difficult for the layman to understand the medical terminology and the result is factual understanding of the major aspects of disease which you will NOT get from the standard home health care books from Johns Hopkins, Harvard, Mayo Clinic, the AMA or even the Merck Home Health handbook. And, unlike the Merck Manual, these books directed to the laity do not contain the diagnostic information upon which physicians decide precisely what disease they are presented with. Yes, there will be much superfluous information which you may never use, but, when you want and need the information about a specific disease, here's where you should start your education. The same holds true for the updated 2018 20th edition. I neglected to mention that this manual also contains a plethora of ancillary information including thorough sections on pediatrics, geriatrics, injuries, bites and stings, patient care, alternative medicine, dietary supplements, rehabilitation, normal test values and even legal issues such as advance directives. Yup, it’s pricey, but it’s always proved to be valuable to me.
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Great reference book
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If you only have one medical resource book in your house, I recommend this one. Very thorough book.
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dabelms of Bensalem
Grantham, US
★★★★★ 5
Good to Have
Format: Hardcover
This is a comprehensive manual. I bought it because of the difference of opinions of different doctors and vets that we received when our cat was sick. We spent over $6,000+ and found out he only had 1 of the 7 symptoms of his diagnosis and the hospital could not find the reason for his weight loss. Many years ago a human Merck Manual helped us discover that the specialist was using one. After coming out of the hospital and during a followup visit, I asked what is the next step to take. I advised him we bought a Merck Manual and can read it just as well as him and was not happy. He sent us to an Electrophysiologist, a speciality we never knew existed. Kitty gained weight again, just needed to peak his appetite with Instinct Rabbit and Duck dry cat food. Apparently, his smell was off and Instinct coats their kibble with the flavor you are buying. It wasn’t easy finding the right one because he is food specific and it must be kibble. We donated all the ones recommended and others we thought he would the rescues. When we first adopted him as a kitten, he was sneezing mucous tinted with blood and vet said he would grow out of it. He did but …. Highly recommend double checking and / or getting a 2nd opinion, human or otherwise.
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Reviewed in the United States on January 26, 2024

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