SKU: 23868752541

Klaire Labs SFI Health Target gb-X Sachets

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Description

Klaire Labs SFI Health Target gb-X SachetsTarget gb X is a probiotic supplement specifically designed to support positive mood by influencing the gut brain axis through the microbiome. It is powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thoughts, and aggressive thoughts. 1 Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood

Target gb-X is a probiotic supplement specifically designed to support positive mood by influencing the gut-brain axis through the microbiome. It is powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thoughts, and aggressive thoughts.1 Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood alterations in otherwise healthy individuals and is therefore considered an important target for interventions.

Target gb-X Mechanism 

Target gb-X with Ecologic BARRIER was specifically designed to influence the gut-brain axis through defined mechanisms including strengthening of the gut barrier function, modulation of cytokines and inflammatory response, production of potentially neuroprotective metabolites, and HPA regulation. Preclinical research emphasized a pronounced shift away from macrophage-produced cytokines to T-lymphocyte-produced cytokines, a reduction in circulating lipopolysaccharide endotoxins, and a marked reduction in transcription of hippocampal genes related to HPA regulation.2 

Probiotics and the Gut-Brain Axis 

The gut-brain axis refers to the bidirectional communication network between the central and autonomic nervous systems and the intestines. Gut-brain communications are mediated by the immune system, endocrine connections such as the hypothalamic-pituitary-adrenal (HPA) axis, and neural pathways involving the enteric nervous system. The gut microbiota is now known to play a pivotal role in gut-brain communications. It is a complex interaction whereas the microbiota engages locally with intestinal cells as well as communicating directly with the central nervous system through neuroendocrine, immune, and metabolic pathways.3 Research into gut-brain mechanisms is rapidly expanding our understanding and serves to inform the development of targeted probiotic formulations. 

Benefits and Features

  • Powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains 
  • Protected by PROBIOACT Technology for optimal efficacy and shelf-stability 
  • Hypoallergenic, non-GMO powder in single-serving sachets 

Clinically shown to support positive mood by influencing the gut-brain axis through the microbiome.

This is a statement of nutritional support. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any diseases. Individual results may vary.
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SKU: 23868752541

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Pam’s Product Picks
Chelsea, US
★★★★★ 4
Durable bone that you can add a spreadable treat to
Color: Blue
Our German Shepherd was 4 months old when we purchased this. She’s going to be 6 months soon. She has been teething really bad. We wanted some way to sooth her pain. This product was just what we needed. We put it in the freezer with some peanut butter in the center on both sides. Once frozen we give to our puppy. She loves it. When we open the freezer she recognizes the ziplock package that it was delivered in which we store it in our freezer. She jumps around until we give it to her. She loves it and it keeps her occupied for a while. It is very durable. I did not notice any smell when we received it. It does not make any noise. The plastic material is safe for animals. To clean I put in the dishwasher. The only reason I did not give it 5 stars is because sometimes the peanut butter gets stuck in it and may need to go through the dishwasher twice which is not a big deal. Or you can hand wash it. I found the dishwasher was best for us. You do not even have to put anything on it, but our pup likes it. I would recommend to others.
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Reviewed in the United States on June 15, 2025
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bill
Dallas, US
★★★★★ 5
Great dog chew toy . Durable and long lasting
Style: Two pack
Durable dog toy Good size Perfect for aggressive chewers Good color choices Lightweight but durable My dogs haven’t destroyed these like they have other toys
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Reviewed in the United States on June 5, 2026
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Amber L.
Carnegie, US
★★★★★ 5
Actually indestructible!
Style: Two pack
I am always leery of items marked indestructible because my 100+ lb. dog chews through anything I buy him. But not this. It's solid plastic that he LOVES to chew on. And I love that there are 2 of them so he can have them in alternative places to play with. The shape and texture seems to entice him and keep him occupied for a few minutes, which is a blessing!
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Reviewed in the United States on April 16, 2026
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Barbara Ellen Large
Charlottesville, US
★★★★★ 5
Great product.He's still chewing on them.That's what I want
Style: Two pack
Bought forever ago and he's still chewing on them.Great product strong dog
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Reviewed in the United States on May 3, 2026
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Crickett
Pawtucket, US
★★★★★ 4
Indestructible
Style: Two pack
Hard on wood floors but lasts forever. Helps keep teeth clean too.
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Reviewed in the United States on March 20, 2026

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