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Description
p57 Recombinant Rabbit mAb (SDT-191-79)Product Specification Host Rabbit Antigen p57 Synonyms Cyclin dependent kinase inhibitor 1C, Cyclin dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2, P57 KIP2 Immunogen Synthetic Peptide Location Nucleus Accession P49918 Clone Number SDT 191 79 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, ICFCM, IP Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage
Product Specification
| Host | Rabbit |
| Antigen | p57 |
| Synonyms | Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2, P57-KIP2 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | P49918 |
| Clone Number | SDT-191-79 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:200 | |
| ICFCM | 1:500 | |
| ICC | 1:500 | |
| IP | 1:50 |
Background
p57 is a cyclin dependent kinase inhibitor protein. Normal p57 expression (strong nuclear staining in villous cytotrophoblasts, intermediate trophoblasts and villous stromal cells) is seen in all gestations that contain maternal genetic material. p57 expression is lost in complete hydatidiform mole, while it is retained in partial hydatidiform moles and nonmolar specimens.
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